In vivo depletion of T-cell subsets in cattle
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Permanent link to this item: http://hdl.handle.net/10568/2829
Internet URL: https://cgspace.cgiar.org/handle/10568/2726
Techniques for in vivo depletion of lymphocytes using monoclonal antibodies have been well documented for murine systems. This model has played an important role in analysing the involvement of various lymphocyte subsets in several immune mechanisms. In mice 600 ug of Ab are generally injected intraperitoneally once a week. In order to study bovine specific immune mechanisms we have attempted to adapt this technology to cattle.