Subunit vaccines for the control of Theileria parva
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Permanent link to this item: http://hdl.handle.net/10568/2863
Internet URL: https://cgspace.cgiar.org/handle/10568/2876
Improvement of the livestock industry in many developing countries has been severely constrained by tick-borne diseases. The major protozoan pathogens responsible for these diseases in cattle are Theileria parva and B. annulata and Babesia bigemina and B. bovis. East Coast fever is of great economic importance throughout eastern, central and southern Africa. Babesiosis has a world-wide distribution. Anaplasmosis is also a disease with significant impact on the cattle industry throughout the world. Heartwater is widespread in sub-Saharan Africa and has been introduced to the Caribbean Islands. All of the above tick-borne pathogens constitute a major impediment to the introduction of highly susceptible Bos Taurus cattle into endemic areas and are the cause of high morbidity and mortality. This review focuses on recent research towards the development of a subunit vaccine against T. parva.