Serum enzyme levels and influencing factors in three indigenous Ethiopian sheep breeds
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Journal of Comparative Clinical Pathology;17(3): 149-155
Permanent link to this item: http://hdl.handle.net/10568/33003
Serum enzymes were studied in 377 apparently healthy sheep from three indigenous sheep breeds of Ethiopia. The effect of breed, age, sex and season on alanine aminotransferase (ALT)/glutamic pyruvic transaminase (GPT), aspartate aminotransferase (AST)/glutamic oxalacetic transaminase (GOT), alkaline phosphatase (ALP) and acid phosphatase (AcP) levels was assessed. The mean serum enzymes levels of the indigenous Menz, Tukur and Wello sheep breeds ranged from 17.2-17.7 IU l-1, AST/GOT from 50.4-56.6 IU l-1, ALP from 93.2-103.9 IU l-1, and AcP from 2.47-2.56 IU l-1, were within the normal range for sheep elsewhere. Season had significant influence on all serum enzymes except for the AcP in Menz breed. Sex had significant effect on AST/GOT for Menz and on ALP for all sheep breeds, with consistently higher values in males than in females. Age was significant only on ALP in the Menz and Tukur breeds. The serum enzyme levels of these indigenous sheep breeds can be used as normal reference values for Ethiopian sheep breeds adapted to similar agro-ecology and production system.