Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions
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Mwangi, D.M., Hopkins, J. and Luckins, A.G. 1995. Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions. Veterinary Parasitology 60(1-2): 45-52
Permanent link to this item: http://hdl.handle.net/10568/35261
Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days after infection, and were also found in dermal lymphatics and in the connective tissue matrix between collagen bundles. Mast cells in the skin obtained 5 days after infection showed evidence of degranulation. These events may play a role during the induction phase of trypanosomal chancres.