Advancing full length genome sequencing for human RNA viral pathogens
MetadataShow full item record
Djikeng, A. and Spiro, D. 2009. Advancing full length genome sequencing for human RNA viral pathogens. Future Virology 4(1): 47–53.
Permanent link to this item: http://hdl.handle.net/10568/68339
In the face of numerous emerging and re-emerging viral threats, large-scale genome sequencing efforts are underway to monitor viral evolution in real-time. To fully appreciate the mechanisms of viral adaptation and evolution, and to also develop reagents and resources for a better molecular diagnosis of emerging and re-emerging viral infections, there has been an increasing effort toward producing full length viral genome sequences. To date, high-throughput platforms have been developed using traditional Sanger-based sequencing and there are currently prospects to apply next generation sequencing methods to develop an ultra high-throughput strategy for viral genome sequencing and analysis.
- ILRI BecA articles