International Livestock Research Institute Livestock genetics and breeding ILRI corporate report highlights 2015–2016 5 Livestock genetics and breeding Application of new breeding Combining improved livestock Investing in African and and genomic approaches genetics with interventions in Asian geneticists leverages leads to more animals that improved animal management biosciences and biotechnology are productive and resilient practices significantly increases for livestock development to disease and change the incomes and nutritional climate security of smallholder farmers Science into practice Adapting the results of high-end laboratory research to the needs of smallholder farmers A new partnership of leading molecular and data scientists from the Roslin Institute, Scotland’s Rural College at the University of Edinburgh and ILRI, in the recently established Centre for Tropical Livestock Genetics and Health, will enable the rapid deployment of technologies and tools to improve the productivity of livestock breeds for smallholder farmers, while preserving animal resilience and resistance to disease in some of the world’s most fragile environments. New genomic tools contribute to more effective vaccines for avian flu As recent disease outbreaks have shown, avian flu can be costly and a serious risk to human health. Using new genomic tools, ILRI and partner scientists in China pioneered the development of special chicken lines that advance understanding of the genetic basis of disease resistance and that will inform future research in discovering more effective vaccines to avian pathogens. Combining the best cattle breeds with improved animal management practices increases household income Using innovative approaches to assess and recommend combinations of genetics and enhanced management practices increased household income by nearly eight times that of traditional breeds and management in Senegal. The findings suggest that future interventions to improve the benefits from dairy production should include improving the availability of high quality semen, offer animal husbandry training to livestock keepers and make credit available for investment in better feed. Profit (USD) per cow per annum Profit from improved breeding and management in Senegal 800 640 The graphic illustrates incomes changes of smallholder farmers 480 in Senegal from employing combinations of breeds—Zebu, 320 Guzerat and Bos taurus—and 160 management approaches. The image was adapted from 0 Marshall et al. 2016. Indigenous Zebu Indigenous Zebu by Guzerat Indigenous Zebu by Bos taurus Poorer Better Poorer Better Poorer Better management management management management management management Breed group and level of animal management DNA sequencing reveals new understanding of the genetics of climate-smart sheep Analysis of the DNA sequences from 77 native sheep in China revealed novel insights into their rapid genetic adaptation to extreme environments. This offers a valuable resource to enable smarter and faster livestock breeding in response to climate change, and confirms the significance of understanding and protecting the unique traits of indigenous livestock. Based on the findings from DNA sequencing of 77 sheep in China, the image depicts the rapid adaption of the animal’s genetic makeup in response to historic changes in climate in the country. (This design, provided courtesy of Ms Ze-Hui Chen, was adapted from Jang 2016) Evidence-based decision-making Transforming dairy opportunities in Ethiopia by enabling new, streamlined insemination processes at scale New technologies and approaches to the mass artificial insemination of cows were tested in two Ethiopian regions by ILRI scientists in 2012, resulting in marked increases in the efficiency of the process. The experiment was subsequently scaled out by national partners, with about 600,000 cows inseminated over a four-year period in four regions. Initially, conception rates were much lower than those achieved in the research trials. Working closely with the authorities, ILRI has recently produced more efficient protocols, identified improved technologies and promoted their uptake together with improved husbandry, resulting in a 50% increase in conception rates. Capacity development Building a critical mass of skilled geneticists to leverage biosciences for livestock development As part of the capacity development undertaken at the Biosciences eastern and central Africa–ILRI Hub, four research fellows and 89 other researchers from across Africa benefited f rom t raining i n t he l atest g enetics and genomics tools to enhance their capacity to tackle the challenges of better animal breeding. A range of multimedia tools, including the Animal Genetics Training Resource (agtr.ilri.org) also boosted the skills base of geneticists, addressing opportunities to improve livestock breeding in tropical regions. This resource has recently been adapted in a number of African and European universities to train masters students on issues related to animal genetic resources in tropical production systems. Key research Key partners for the work reported here Caixia, G. 2015. Establishment of six homozygous MHC-B Association for Strengthening Agricultural Research in haplotype populations associated with susceptibility to Eastern and Central Africa • Bangladesh Agricultural Marek’s disease in Chinese specific pathogen-free BWEL University • Chinese Academy of Agricultural Sciences chickens. Infection, Genetics and Evolution 29:15–25. • Diversity Arrays Technology Ltd • Ethiopian Institute of Agricultural Research • Ethiopia Ministry of Livestock Ieda, N. et al. 2015. Characterization of smallholder and Fisheries • Farm Input Promotions Africa • Federal pig breeding practices within a rural commune University of Agriculture in Abeokuta, Nigeria • Green of North Central Vietnam. Tropical Animal Dreams Tech Ltd • Heifer International • International Health and Production 47(6):1005–1016. Center for Agricultural Research in the Dry Areas • Lv, F.H. et al. 2015. Mitogenomic meta-analysis identifies Institut de l’Environnement et de Recherches Agricoles • two phases of migration in the history of Eastern Eurasian International Institute of Tropical Agriculture • International sheep. Molecular Biology and Evolution 32(10):2515–2533. Food Policy Research Institute • International Potato Kiome, R. 2015. A strategic framework for transgenic Center • Jomo Kenyatta University of Agriculture and research and product development in Africa: Report of a Technology • Kenya Agricultural and Livestock Research CGIAR study. ILRI Project Report. Nairobi, Kenya: ILRI. Organization • Kenya Ministry of Agriculture, Livestock and Fisheries • Kenya State Department of Livestock • Land Marshall, K. et al. 2016. Pig breeds and breeding O’Lakes International Development • Lilongwe University operations in Nghe An province, Vietnam, of Agriculture and Natural Resources • LUKE-Finland • with a focus on the smallholder pig sector. ILRI National Animal Production Research Institute, Nigeria • Research Report 41. Nairobi, Kenya: ILRI. National Artificial Insemination Centre, Ethiopia • National Marshall, K. et al. 2016. Better dairy cattle breeds and better Institute of Animal Husbandry, Vietnam • Neighbors management can improve the livelihoods of the rural poor Initiative Alliance • Nelson Mandela African Institution in Senegal. ILRI Research Brief 65. Nairobi, Kenya: ILRI. of Science and Technology • New York University • PICO-Eastern Africa • Roslin Institute at the University of Mbuku, S.M. et al. 2015. Optimum crossbreeding systems Edinburgh • Scotland’s Rural College • Swedish University for goats in low-input livestock production system in of Agricultural Sciences • Tanzania Livestock Research Kenya. Small Ruminant Research 123(1):55–61. Institute • TechnoServe • Sokoine University of Agriculture Mingyan, Y. et al. 2016. Cloning of the African indigenous • University of Cape Town • University of Agriculture, cattle breed Kenyan Boran. Animal Genetics 47(4):510–511. Pakistan • Universidad Nacional Agraria Managua • University of Natural Resources and Life Sciences-BOKU Okeyo, A.M. et al. 2015. African indigenous cattle: Unique • University of Nicaragua • University of New England, genetic resources in a rapidly changing world. Asian- Australia • University of Peradeniya • University of Australasian Journal of Animal Sciences 28(7):911–921. Seoul • Wageningen University • Western Highlands Wondmeneh, E. et al. 2016. Comparison of different Agriculture and Forestry Science Institute, Vietnam. poultry breeds under station and on-farm conditions in Ethiopia. Livestock Science 183:72–77. CGIAR research programs Yang, J. 2016.Whole-genome sequencing of native Livestock and Fish sheep provides insights into rapid adaptations to extreme environments. Mol Biol Evol. pii: msw129. Contact König, E.Z. et al. 2016. Participatory definition of breeding objectives for sheep breeds under pastoral systems— Steve Kemp, ILRI Kenya the case of Red Maasai and Dorper sheep in Kenya. s.kemp@cgiar.org Tropical Animal Health and Production 48(1): 9–20. ILRI thanks all donors and organizations which globally supported its work through their contributions to the CGIAR system Patron: Professor Peter C Doherty AC, FAA, FRS Animal scientist, Nobel Prize Laureate for Physiology or Medicine–1996 Box 30709, Nairobi 00100 Kenya ilri.org Box 5689, Addis Ababa, Ethiopia Phone +254 20 422 3000 better lives through livestock Phone +251 11 617 2000 Fax +254 20 422 3001 Fax +251 11 667 6923 Email ilri-kenya@cgiar.org ILRI is a CGIAR research centre Email ilri-ethiopia@cgiar.org ILRI has offices in East Africa • South Asia • Southeast and East Asia • Southern Africa • West Africa ILRI corporate report highlights 2015–2016 This publication is copyrighted by the International Livestock Research Institute (ILRI). It is licensed for use under the Creative Commons Attribution 4.0 International Licence. December 2016