Evaluation of the 4q32-34 Locus in European familial pancreatic cancer

Citation

Earl, J.; Yan, L.; Vitone, L.J.; Risk, J.; Kemp, S.J.; McFaul, C.; Neoptolemos, J.P.; Greenhalf, W.; Kress, R.; Sina-Frey, M.; Hahn, S.; Rieder, H.; Bartsch, D.K. 2006. Evaluation of 4q-32-34 Locus in European familial pancreatic cancer. Cancer Epidemiological Biomarkers & Prevention 15(10):1948-1955.

Abstract/Description

Background: Familial pancreatic cancer (FPC) describes a group of families where the inheritance of pancreatic cancer is consistent with an autosomal-dominant mode of inheritance. The 4q32-34 region has been previously identified as a potential locus for FPC in a large American family.

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