Susceptibility of different chicken lines to H7N1 highly pathogenic avian influenza virus and the role of Mx gene polymorphism coding amino acid position 631

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cg.identifier.doihttps://doi.org/10.1016/j.virol.2008.07.022en
cg.issn0042-6822en
cg.issue1en
cg.journalVirologyen
cg.subject.ilriDISEASE CONTROLen
cg.subject.ilriANIMAL DISEASESen
cg.subject.ilriGENETICSen
cg.volume380en
dc.contributor.authorSironi, L.en
dc.contributor.authorWilliams, J.L.en
dc.contributor.authorMoreno Martin, A.M.en
dc.contributor.authorRamelli, P.en
dc.contributor.authorStella, A.en
dc.contributor.authorWeigend, S.en
dc.contributor.authorLombardi, G.en
dc.contributor.authorCordioli, P.en
dc.contributor.authorMariani, P.en
dc.contributor.authorHan Jianlinen
dc.date.accessioned2010-05-11T17:34:13Zen
dc.date.available2010-05-11T17:34:13Zen
dc.identifier.urihttps://hdl.handle.net/10568/1501
dc.titleSusceptibility of different chicken lines to H7N1 highly pathogenic avian influenza virus and the role of Mx gene polymorphism coding amino acid position 631en
dcterms.abstractFive chicken lines were experimentally infected with a HPAI H7N1 virus, to examine the variation in susceptibility to infection. Three lines showed high susceptibility to the virus, while two showed some resistance, with 7 out of 20, and 11 out of 15 birds, respectively, remaining healthy and surviving the experimental infection. Genotyping for the G/A polymorphism at position 2032 of Mx cDNA showed that one line was fixed for the G allele, and two were segregating for A and G alleles. Birds in the other two lines were selected to be fixed for the A allele. Statistical analyses indicated that the Mx genotype did not affect the clinical status or the time course of infection after viral inoculation.en
dcterms.accessRightsLimited Access
dcterms.bibliographicCitationSironi, L.; Williams, J.L.; Moreno-Martin, A.M.; Ramelli, P.; Stella, A.; Jianlin, H.; Weigend, S.; Lombardi, G.; Cordioli, P.; Mariani, P. 2008. Susceptibility of different chicken lines to H7N1 highly pathogenic avian influenza virus and the role of Mx gene polymorphism coding amino acid position 631. Virology 380(1):52-158.en
dcterms.extentp. 152-156en
dcterms.issued2008-10en
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherElsevieren
dcterms.subjectanimal diseasesen
dcterms.subjectdisease controlen
dcterms.subjectchickensen
dcterms.typeJournal Article

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