Seroepidemiological survey of Rift Valley fever virus in ruminants in Garissa, Kenya

Simple item page
cg.authorship.typesCGIAR and developing country institute
cg.authorship.typesCGIAR and advanced research institute
cg.contributor.affiliationUniversity of Nairobi
cg.contributor.affiliationColorado State University
cg.contributor.affiliationKenya Medical Research Institute
cg.contributor.affiliationWashington State University
cg.contributor.affiliationInternational Livestock Research Institute
cg.contributor.crpAgriculture for Nutrition and Health
cg.coverage.countryKenya
cg.coverage.iso3166-alpha2KE
cg.coverage.regionAfrica
cg.coverage.regionEastern Africa
cg.creator.identifierBernard Bett: 0000-0001-9376-2941
cg.howPublishedFormally Published
cg.identifier.doihttps://doi.org/10.1089/vbz.2016.1988
cg.isijournalISI Journal
cg.issn1530-3667
cg.issue2
cg.journalVector-Borne and Zoonotic Diseases
cg.reviewStatusPeer Review
cg.subject.ilriANIMAL DISEASES
cg.subject.ilriCATTLE
cg.subject.ilriEPIDEMIOLOGY
cg.subject.ilriGOATS
cg.subject.ilriRVF
cg.subject.ilriSHEEP
cg.subject.ilriSMALL RUMINANTS
cg.subject.ilriZOONOTIC DISEASES
cg.volume17
dc.contributor.authorNanyingi, M.O.
dc.contributor.authorMuchemi, G.M.
dc.contributor.authorThumbi, Samuel M.
dc.contributor.authorAde, F.
dc.contributor.authorOnyango, C.O.
dc.contributor.authorKiama, S.G.
dc.contributor.authorBett, Bernard K.
dc.date.accessioned2017-01-16T20:07:43Zen
dc.date.available2017-01-16T20:07:43Zen
dc.identifier.urihttps://hdl.handle.net/10568/78800
dc.titleSeroepidemiological survey of Rift Valley fever virus in ruminants in Garissa, Kenyaen
dcterms.abstractIntroduction: Rift Valley fever (RVF) is a vector-borne zoonotic disease caused by phlebovirus in the family Bunyaviridae. In Kenya, major outbreaks occurred in 1997–1998 and 2006–2007 leading to human deaths, huge economic losses because of livestock morbidity, mortality, and restrictions on livestock trade. Aim: This study was conducted to determine RVF seroprevalence in cattle, sheep, and goats during an interepidemic period in Garissa County in Kenya. Methods: In July 2013, we performed a cross-sectional survey and sampled 370 ruminants from eight RVF-prone areas of Garissa County. Rift Valley fever virus (RVFV) antibodies were detected using a multispecies competitive enzyme-linked immunosorbent assay. Mixed effect logistic regression models were used to determine the association between RVF seropositivity and species, sex, age, and location of the animals. Results: A total of 271 goats, 87 sheep, and 12 cattle were sampled and the overall immunoglobulin G seroprevalence was 27.6% (95% CI [23–32.1]). Sheep, cattle, and goats had seroprevalences of 32.2% (95% CI [20.6–31]), 33.3% (95% CI [6.7–60]), and 25.8% (95% CI [22.4–42]), respectively. Seropositivity in males was 31.8% (95% CI [22.2–31.8]), whereas that of females was 27% (95% CI [18.1–45.6]). Conclusions: The high seroprevalence suggests RVFV circulation in domestic ruminants in Garissa and may be indicative of a subclinal infection. These findings provide evidence of RVF disease status that will assist decision-makers to flag areas of high risk of RVF outbreaks and prioritize the implementation of timely and cost-effective vaccination programs.en
dcterms.accessRightsLimited Access
dcterms.audienceScientists
dcterms.bibliographicCitationNanyingi, M.O., Muchemi G.M., Thumbi, S.M., Ade, F., Onyango, C.O., Kiama, S.G. and Bett, B. 2017. Seroepidemiological survey of Rift Valley fever virus in ruminants in Garissa, Kenya. Vector-Borne and Zoonotic Diseases 17(2): 141–146.en
dcterms.extentp. 141-146
dcterms.issued2017-02
dcterms.languageen
dcterms.licenseCopyrighted; all rights reserved
dcterms.publisherMary Ann Liebert Inc
dcterms.subjectsheepen
dcterms.subjectgoatsen
dcterms.subjectanimal diseasesen
dcterms.subjectvirusesen
dcterms.subjectresearchen
dcterms.subjectzoonosesen
dcterms.typeJournal Article

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.87 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ILRI articles in journals
CRP A4NH outputs
ILRI animal and human health program outputs (2017–2024)