Spatial and temporal distribution of Taenia solium and its risk factors in Uganda

Simple item page
cg.authorship.typesCGIAR and developing country instituteen
cg.authorship.typesCGIAR and advanced research instituteen
cg.contributor.affiliationInternational Livestock Research Instituteen
cg.contributor.affiliationMinistry of Health, Ugandaen
cg.contributor.affiliationWorld Health Organizationen
cg.contributor.affiliationUniversity of Liverpoolen
cg.contributor.affiliationImperial College Londonen
cg.contributor.affiliationSCI Foundationen
cg.contributor.donorFederal Ministry for Economic Cooperation and Development, Germanyen
cg.contributor.donorSCI Foundationen
cg.contributor.donorBayer AG and Mercken
cg.coverage.countryUganda
cg.coverage.iso3166-alpha2UG
cg.coverage.regionAfrica
cg.coverage.regionEastern Africa
cg.creator.identifierNICHOLAS NGWILI: 0000-0002-3940-4438
cg.creator.identifierDerrick Noah Sentamu: 0000-0002-6151-4852
cg.creator.identifierMichel Dione: 0000-0001-7812-5776
cg.creator.identifierLian Thomas: 0000-0001-8447-1210
cg.howPublishedFormally Publisheden
cg.identifier.doihttps://doi.org/10.1016/j.ijid.2023.02.001en
cg.isijournalISI Journalen
cg.issn1201-9712en
cg.journalInternational Journal of Infectious Diseasesen
cg.reviewStatusPeer Reviewen
cg.speciesTaenia soliumen
cg.subject.ilriONE HEALTHen
cg.subject.ilriZOONOTIC DISEASESen
cg.subject.impactAreaNutrition, health and food security
cg.subject.sdgSDG 2 - Zero hungeren
cg.volume129en
dc.contributor.authorNgwili, Nicholasen
dc.contributor.authorSentamu, Derrick N.en
dc.contributor.authorKorir, M.en
dc.contributor.authorAdriko, M.en
dc.contributor.authorBeinamaryo, P.en
dc.contributor.authorDione, Michel M.en
dc.contributor.authorKaducu, J.M.en
dc.contributor.authorMubangizi, A.en
dc.contributor.authorMwinzi, P.N.en
dc.contributor.authorThomas, Lian F.en
dc.contributor.authorDixon, M.A.en
dc.date.accessioned2023-02-26T13:05:16Zen
dc.date.available2023-02-26T13:05:16Zen
dc.identifier.urihttps://hdl.handle.net/10568/129050
dc.titleSpatial and temporal distribution of Taenia solium and its risk factors in Ugandaen
dcterms.abstractBackground The lack of sub-national mapping of the zoonotic cestode Taenia solium in endemic countries presents a major challenge to achieving intensified T. solium control milestones, as outlined in the “World Health Organization neglected tropical disease roadmap by 2030”. We conducted a mapping study in Uganda, considered to be endemic, to identify sub-national high-risk areas. Methods T. solium prevalence data, adjusted for diagnostic sensitivity and specificity in a Bayesian Framework, were identified through a systematic review. Spatial autocorrelation and interpolation techniques were used to transform Demographic and Health Survey cluster-level sanitation and poverty indicators, overlaid onto a pig density map for Uganda into modelled porcine cysticercosis (PCC) risk maps. Findings Sixteen articles (n = 11 PCC and n = 5 human cysticercosis (HCC) and/or human taeniasis) were included in the final analysis. HCC observed prevalence ranged from 0.01% – 6.0 % (Confidence Interval (CI) range: 0.004 – 11.4%), while adjusted PCC ranged from 0.3 – 93.9% (uncertainty interval range: 0 – 99.8%). There was substantial variation in the modelled PCC risk factors and prevalence across Uganda and over time. Interpretation High PCC prevalence and moderate HCC exposure estimates indicate the need for urgent implementation of T. solium control efforts in Uganda.en
dcterms.accessRightsOpen Access
dcterms.audienceAcademicsen
dcterms.audienceScientistsen
dcterms.bibliographicCitationNgwili, N., Sentamu, D.N., Korir, M., Adriko, M., Beinamaryo, P., Dione, M.M., Kaducu, J.M., Mubangizi, A., Mwinzi, P.N., Thomas, L.F. and Dixon, M.A. 2023. Spatial and temporal distribution of Taenia solium and its risk factors in Uganda. International Journal of Infectious Diseases 129: 274–284.en
dcterms.extent274-284en
dcterms.issued2023-04
dcterms.languageen
dcterms.licenseCC-BY-NC-ND-4.0
dcterms.publisherElsevieren
dcterms.subjectzoonosesen
dcterms.subjectone health approachen
dcterms.typeJournal Article

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ILRI articles in journals
ILRI animal and human health program outputs (2017–2024)
ILRI policies, institutions and livelihoods program outputs (2017–2024)
One Health Research, Education and Outreach Centre in Africa (OHRECA)